発表論文

2016年

1. Yamada H, Kikuchi S, Hakozaki M, Motodate K, Nagahora N, Hirose M. 8-Hydroxyeicosapentaenoic Acid Decreases Plasma and Hepatic Triglycerides via Activation of Peroxisome Proliferator-Activated Receptor Alpha in High-Fat Diet-Induced Obese Mice. Journal of Lipids,2016:7498508

2015年

1. Yano A,  Ito K, Miwa Y, Kanazawa Y, Chiba A, Iigo Y, Kashimoto Y, Kanda A, Murata S, Makino M. The peptide vaccine combines with prior immunization of a conventional diphtheria-tetanus toxoid vaccine induced amyloid beta binding antibodies on cynomolgus monkeys and guinea pigs. J Immun Res 2015:ID786501

2014

1. Yamada H, Oshiro E, Kikuchi S,Hakozaki M, Takahashi H, Kimura K. Hydroxyeicosapentaenoic acids from the Pacific krill show high ligand activities for PPARs. J Lipid Res. (2014) 55(5):895-904.

 2. 山田秀俊 イサダ由来の8-ヒドロキシエイコサペンタエン酸(8-HEPE)による脂肪燃焼促進作用 New Food Industry (2014-09) 56(9):29-34

 3. Yamada H, Kikuchi S, Inui T,Takahashi H, Kimura KI. Gentiolactone, a secoiridoid dilactone from Gentiana triflora, inhibits TNF-a, iNOS and Cox-2 mRNA expression and blocks NF-κB promoter activity in murine macrophages. PLoS ONE (2014) 9(11): e113834.

 4. Kurose T, SaitoY, Nakagawa Y, Yano A, ItoK, Kawarasaki Y. Secretory expression of Lentinula edodes intracellular laccase by yeast high-cell-density system: Sub-milligram production of difficult-to-express secretory protein. J Biosci Bioeng (2014) 117(6):659-63.

5. 山田秀俊 イサダ(ツノナシオキアミ)由来の新たな抗肥満成分:8-HEPE BIO INDUSTRY (2014) 31(12):46-51

2013

1. Yano A, Abe A, Aizawa F, Yamada H,Minami K, Matsui M, Kishi M. The Effect of Eating Sea Cucumber Jelly on Candida Load in the Oral Cavity of Elderly Individuals in a Nursing Home.  Mar. Drugs (2013) 11:4993-5007.

 2. Yano A, Miwa Y, Kanazawa Y, Ito K,Makino M, Imai S, Hanada N, Nisizawa T. A novel method for enhancement of peptide vaccination utilizing T-cell epitopes from conventional vaccines. Vaccine (2013) 31(11):1510-1515.

3. Nakade K, Nakagawa Y, Yano A, Konno N, Sato T, Sakamoto Y. Effective induction of pblac1 laccase by copper ion in Polyporus brumalis ibrc05015. Fungal. Biol. (2013) 117(1):52-61.  

2012

1. Sadzuka Y, Sugiyama I,Miyashita M, Ueda T, Kikuchi S, Oshiro E, Yano AYamada H. Beneficial effects by intake of Euphausiacea pacifica on high-fat diet-induced obesity. Biol. Pharm. Bull. (2012) 35:568-572.

2. Yano A, Kikuchi S, TakahashiT, Kohama K, Yoshida Y. Inhibitory effects of the phenolic fraction from the pomace of Vitis coignetiae on biofilm formation by Streptococcus mutansArch. Oral Biol. (2012) 57:711-719.

3. Yano A, Konno N, Imai S, KatoH. Inhibitory effects of polysaccharides on the cariogenic activities of Streptococcus mutansBiosci. Biotechnol. Biochem. (2012) 76:2313-2316.

4. Takahashi H,Yamada H, Yoshida C, Imamura T. Modification of light quality improves the growth and medicinal quality of clonal plantlets derived from the herbal plant Gentiana. Plant Biotechnology (2012) 29(3):315-318.

5. Kimata K, Yamaguchi M, Saito Y, Hata H, Miyake K, Yamane T, Nakagawa Y, Yano A, Ito K, Kawarasaki Y. High cell-density expression system: A novel method for extracellular production of "difficult-to-express" proteins. J. Biosci. Bioeng. (2012) 113(2):154-159.

2011

1. Yamada H, Ueda T, Yano A. Water-Soluble Extract of Pacific Krill Prevents Triglyceride Accumulation in Adipocytes by Suppressing PPARγ and C/EBPα Expression. PLoS ONE. (2011) 6: e21952. 

2. Kimata K, Yamaguchi M, Saito Y, HataH, Miyake K, Yamane T, Nakagawa Y, Yano A, Ito K, and Kawarasaki Y. High cell-density expression system: A novel method for extracellular production of "difficult-to-express" proteins. J Biosci Bioeng. (2012) 113(2):154-9.

2010

1. Sasaki-Imamura T, Yano A, Yoshida Y. Production of indol from L-tryptophan and effects of these compounds on biofilm formation by Fusobacterium nucleatum ATCC25586. App. Environ. Microbiol.  (2010) 76:4260-4268.

2. Nakade K, Nakagawa Y, Yano A, Sato T, Sakamoto Y. Characterization of an extracellular laccase, PbLac1, purified from Polyporus brumalisFungal Biology  (2010) 114:609-618.

3. Nakagawa Y, Sakamoto Y, Kikuchi S, Sato T, Yano A. A chimeric laccase with hybrid properties of the parental Lentinula edodes laccases. Microbiological Research. (2010) 165:392-401.

4. Nakagawa Y, Kikuchi S, Sakamoto Y, Yano A. Identification and characterization of CcCTR1, a copper uptake transporter-like gene, in Coprinopsis cinereaMicrobiological Research. (2010) 165:276-287.

5. Yano A, Kikuchi S, YamashitaY, Sakamoto Y, Nakagawa Y, Yoshida Y. The inhibitory effects of mushroom extracts on sucrose-dependent oral biofilm formation. Appl. Microbiol. Biotechnol. (2010) 86(2):615-623. 

2009

1. Yano A, Kikuchi S, Nakagawa Y,Sakamoto Y, Sato T. Secretory expression of the non-secretory-type Lentinula edodes laccase by Aspergillus 

      oryzaeMicrobiolgical Research.(2009) 164:642-649.

2008

1. Sakamoto Y, Keiko N, Yano A, Nakagawa Y, Hirano T, Irie T, Watanabe H, Nagai M, Sato T. Heterologous expression of lcc1 from Lentinula edodes in tobacco BY-2 cells results in the production an active, secreted form of fungal laccase. Appl. Microbiol. Biotechnol. (2008) 79:971-980.

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